Anthrax Lethal Factor Mouse anti-Bacteria, Clone: 5F502.2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA141075
Suggested positive control: recombit protein.Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxic entry into cells. PA is secreted from Bacillus anthracis as an 83 kDa (PA83) protein which is cleaved by furin protease, releasing a 20 kDa fragment. The 63 kDa portion (PA63) of the cleavage product forms a heptamer, which binds the toxins LF and EF. This complex enters via receptor-mediated endocytosis where LF and EF exert their toxic effects.
|Anthrax Lethal Factor|
|PBS with 0.05% BSA and 0.05% sodium azide|
|Synthetic peptide corresponding to residues 779-792 of the anthrax LF protein.|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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