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Anthrax Lethal Factor Mouse anti-Bacteria, Clone: 5F502.2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA141075

Catalog No. 01-676-460


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Description

Description

Suggested positive control: recombit protein.

Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxic entry into cells.  PA is secreted from Bacillus anthracis as an 83 kDa (PA83) protein which is cleaved by furin protease, releasing a 20 kDa fragment. The 63 kDa portion  (PA63) of the cleavage product forms a heptamer, which binds the toxins LF and EF. This complex enters via receptor-mediated endocytosis where LF and EF exert their toxic effects.
Specifications

Specifications

Anthrax Lethal Factor
Monoclonal
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Anthrax LF
Synthetic peptide corresponding to residues 779-792 of the anthrax LF protein.
Protein G
RUO
Antibody
Monoclonal
Western Blot
5F502.2
Unconjugated
Liquid
Mouse
IgG1, kappa
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
Bacteria
Documents
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