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Anthrax Protective Antigen Rabbit anti-Bacteria, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141128

Catalog No. 01-675-708


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Description

Description

Suggested positive control: PA recombit protein.

Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxic entry into cells.  PA is secreted from Bacillus anthracis as an 83 kDa (PA83) protein which is cleaved by furin protease, releasing a 20 kDa fragment. The 63 kDa portion  (PA63) of the cleavage product forms a heptamer, which binds the toxins LF and EF. This complex enters via receptor-mediated endocytosis where LF and EF exert their toxic effects.
Specifications

Specifications

Anthrax Protective Antigen
Polyclonal
whole serum diluted in PBS with 0.05% BSA and 0.05% sodium azide
Anthrax PA
Synthetic peptide corresponding to residues 186-192 of Anthrax Pa.
200 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
Bacteria
Western Blot
Unconjugated
Liquid
Rabbit
IgG
RUO
Antibody
Polyclonal
Documents
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