AP2 alpha Rabbit anti-Human, Mouse, Ovine, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA125327
PA1-25327 detects AP2 alpha from human samples. PA1-25327 is expected to cross react with mouse (94% conserved), rat (94% conserved), chicken (88% conserved), and ovine (94% conserved) due to sequence homology. PA1-25327 has been successfully used in Western blot and immunofluorescence procedures. The PA1-25327 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues S(420) H T D N N A K S S D K E E K H R K(437) of human AP2 alpha. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene is a transcription factor that binds the consensus sequence 5 ft.-GCCNNNGGC-3 ft.. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
|Synthetic peptide, conjugated to KLH, corresponding to residues S(420) H T D N N A K S S D K E E K H R K(437) of human AP2 alpha.|
|Antigen affinity chromatography|
|Human, Mouse, Ovine, Rat|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4|
|P05549, P34056, Q9N0N3, P58197|
|AP-2, AP-2alpha, AP2TF, BOFS, FLJ51761, TFAP2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|21418, 306862, 443109, 7020|
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