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AP3B2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521163

Catalog No. PIPA521163


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Description

Description

A suggested positive control is rat brain tissue lysate. PA5-21163 can be used with blocking peptide PEP-1277.

The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.
Specifications

Specifications

AP3B2
Polyclonal
Unconjugated
AP3B2
Liquid
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
11775, 308777, 8120
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q13367, Q9JME5
AP3B2
An 18 amino acid peptide near the amino terminus of human AP3B2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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