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AP3M1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521162

Catalog No. PIPA521162


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Description

Description

A suggested positive control is human brain tissue lysate. PA5-21162 can be used with blocking peptide PEP-1276.

The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.
Specifications

Specifications

AP3M1
Polyclonal
Unconjugated
AP3M1
Liquid
AP3M1
A 15 amino acid peptide near the carboxy terminus of human AP3M1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9Y2T2, Q9JKC8, P53676
AP-3 adapter complex mu3A subunit; AP-3 complex subunit mu-1; adapter-related protein complex 3 mu-1 subunit; clathrin adaptor complex AP3, mu-3A subunit; mu-adaptin 3A; mu3A-adaptin
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
171126, 26985, 55946
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