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Protein APC, Polyclonal, Invitrogen™
Description
This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Specifications
Specifications
| Antigen | APC |
| Applications | Immunohistochemistry (Paraffin), Immunoprecipitation |
| Classification | Polyclonal |
| Concentration | 0.2mg/mL |
| Conjugate | Unconjugated |
| Gene | APC |
| Gene Accession No. | P25054, Q61315 |
| Gene Alias | Adenomatous Polyposis Coli, APC, DP2, DP2.5, DP3, FAP, FPC, GS |
| Gene Symbols | APC |
| Host Species | Rabbit |
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