ATG4A Mouse anti-Human, Mouse, Clone: 514914, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524225
In direct ELISAs and Western blots, no cross-reactivity with recombit human ATG4B is observed. Reconstitute at 0.5 mg/mL in sterile PBS.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some maligt tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
|PBS with 5% trehalose and No Preservative|
|Cysteine protease APG4A, Autophagy 4 homolog A, hAPG4A, Autophagin-2, Autophagy-related cysteine endopeptidase 2, AUT-like 2 cysteine endopeptidase, APG4A, AUTL2, ATG4A|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|Sf 21-derived recombit human ATG4A isoform 1 Glu2-Val398|
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