APOE Goat anti-Human, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against recombinant APOE.

Manufacturer:  Abnova Corporation PAB14301

Catalog No. 89-116-987

Description

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq

Specifications

• Antigen: APOE
• Conjugate: Unconjugated
• Dilution: Western Blot (1:5000-1:40000) ELISA (1:5000-1:40000) The optimal working dilution should be determined by the end user.
• Gene: APOE
• Gene Alias: AD2|LPG|MGC1571|apoprotein
• Host Species: Goat
• Quantity: 100 ug
• Storage Requirements: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Test Specificity: This antibody specifically binds to human APOE.

• Applications: ELISA, Western Blot
• Description: Goat polyclonal antibody raised against recombinant APOE.
• Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
• Format: Liquid
• Gene Symbols: APOE
• Immunogen: Recombinant protein corresponding to APOE.
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 348
• Target Species: Human

For Research Use Only