APOE Goat anti-Human, Polyclonal Antibody, Abnova
Goat polyclonal antibody raised against recombinant APOE.
Manufacturer: Abnova Corporation PAB14301
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
|Western Blot (1:5000-1:40000) ELISA (1:5000-1:40000) The optimal working dilution should be determined by the end user.|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody specifically binds to human APOE.|
|ELISA, Western Blot|
|Goat polyclonal antibody raised against recombinant APOE.|
|In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)|
|Recombinant protein corresponding to APOE.|
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