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APOE Goat anti-Human, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA126902

Catalog No. PA126902


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Description

Description

PA1-26902 detects Apolipoprotein E from human samples. PA1-26902 has been successfully used in immunohistochemistry (paraffin), ELISA, immunoprecipitation and Western blot procedures. The PA1-26902 immunogen is purified, full length, native human protein. Store at 4°C short term. For extended storage, aliquot and store at -20°C or below. Avoid freeze/thaw cycles.

Chylomicron remts and very low density lipoprotein (VLDL) remts are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remts.
Specifications

Specifications

APOE
Polyclonal
Unconjugated
APOE
Liquid
APOE
Purified, full length, native human protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1 mg/mL
0.125M sodium borate with 5mM EDTA and 0.01% sodium azide; pH 8
P02649
AD2, LDLCQ5, LPG, MGC1571
Goat
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
348
Documents
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