Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

APP Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of APP.

Manufacturer:  Abnova Corporation PAB4899

Catalog No. 89-024-843


Add to cart

Description

Description

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq

Specifications

Specifications

APP
Unconjugated
ELISA (1:1000) Western Blot (1:50-100) The optimal working dilution should be determined by the end user.
APP
AAA|ABETA|ABPP|AD1|APPI|CTFgamma|CVAP|PN2
Rabbit
400 uL
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human
ELISA, Western Blot
Rabbit polyclonal antibody raised against synthetic peptide of APP.
In PBS (0.09% sodium azide)
Liquid
APP
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human APP.
RUO
Primary
351
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit