Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Aralar Mouse anti-Human, Unlabeled, Clone: 8, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 611162

Catalog No. BDB611162

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.



Mitochondria are the primary sites of ATP production within the cell. They contain two different membranes, the outer membrane and the inner membrane. The outer membrane contains porins which form pores in the membrane and render it highly permeable. The inner membrane is less permeable and contains a high protein-to-lipid ratio. This membrane contains a number of carrier proteins that mediate metabolite transport. These belong to a superfamily of related proteins that are found in S. cerevisiae, C. elegans, and several mammalian
species. Aralar, a human member of this family, is expressed in the mitochondria within heart, skeletal muscle, and brain. Its C-terminal half resembles proteins of the mitochondrial solute carrier superfamily and its N-terminal portion contains four putative Ca2+;-binding EF-hand domains. The presence of the EF-hands in Aralar make it a close relative of the large family of Ca2+;-binding proteins that includes calmodulin and myosin light chain. Aralar is thought to function as a Ca2+;-regulated mitochondrial anion carrier or as a Ca2+; and anion cotransporter since it is expressed primarily in tissues where cell function relies heavily on Ca2+;- signaling.

Host Species: Mouse
Clone: 8
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Aralar aa. 1-119
Formula Weight [Chemical]: 70kDa

Immunofluorescence, Western Blotting



Immunofluorescence, Western Blot
Affinity Purified
Human Aralar aa. 1-119
Cell Biology
Product Certifications


Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit