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Arc Mouse, Unlabeled, Clone: 40, BD

Mouse Monoclonal Antibody

$204.00 - $360.00

Specifications

Antigen Arc
Isotype IgG1
Immunogen Rat Arc aa. 264-385
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB612602
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BD Biosciences
612602
50μg
Each for $204.00
Add to cart
 
BDB612603
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BD Biosciences
612603
150μg
Each for $360.00
Add to cart
 
Description

Description

Immediate early genes (IEGs) are the first to be transcribed upon cellular stimulation. Two groups of these genes have been characterized: those which encode transcription factors that indirectly influence cellular activity, and those which encode effector proteins that directly affect cellular activity. Arc (Activity-Regulated Cytoskeleton-associated protein) encodes an effector protein associated with the actin cytoskeletal matrix. In activated neurons of the hippocampus, Arc gene expression is rapidly induced. Arc protein is concentrated in the actin cortex,
adjacent to the plasma membrane of the cell body and dendrites. Arc has a putative role in the maintenance of neuronal plasticity and in activity-dependent changes in dendrite function. Cocaine and D2 receptor antagonists are known to trigger the production and localization of Arc to dendrites and neuronal cell bodies.

Western Blotting

Specifications

Specifications

Arc
Rat Arc aa. 264-385
Unconjugated
Cell Biology
Mouse
Affinity Purified
Monoclonal
Activity-Regulated Cytoskeleton-associated protein
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
40
250μg/mL
Store undiluted at -20°C.
SDS
Product Certifications

For Research Use Only.

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