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ARHGAP18 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520893

Catalog No. PIPA520893


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Description

Description

A suggested positive control is NIH-3T3 cell lysate. PA5-20893 can be used with blocking peptide PEP-1007.

ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.
Specifications

Specifications

ARHGAP18
Polyclonal
Unconjugated
ARHGAP18
Liquid
ARHGAP18
A 15 amino acid peptide near the carboxy terminus of human ARHGAP18.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q8N392, Q8K0Q5
MacGAP, bA307O14.2; rho GTPase-activating protein 18; rho-type GTPase-activating protein 18
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
293947, 73910, 93663
Documents
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