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anti-CTLA-4, FITC, Clone: 1B8, Novus Biologicals™

Manufacturer:  Novus Biologicals NBP128066

Catalog No. NBP128066

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Specifications

Specifications

CTLA-4
1B8
FITC
PBS with 0.05% Sodium Azide
CD, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
Armenian Hamster
IgG
0.25 mg
Store at 4C. Do not freeze.
Monoclonal
This antibody recognises mouse CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.
Flow Cytometry, In vitro assay
0.5mg/mL
Flow Cytometry <= 3 ug/10^6 cells, In vitro assay
Purified
CTLA4
Extracellular portion of mouse CD152 fused to a mouse IgG2a.
Protein A or G purified
RUO
Primary
1493
Mouse
Documents
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