EMR3 Antibody (3D7) - BSA Free, Novus Biologicals™

Armenian Hamster Monoclonal Antibody

Supplier:  Novus Biologicals NB10065935

Catalog No. NB10065935

Description

EMR3 Monoclonal specifically detects EMR3 in Human samples. It is validated for Flow Cytometry, Immunoprecipitation.

Specifications

• Antigen: EMR3
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry 1:50-1:200, Immunoprecipitation 1:10-1:500
• Gene Alias: egf-like module containing, mucin-like, hormone receptor-like 3, EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3, egf-like module-containing mucin-like receptor 3
• Host Species: Armenian Hamster
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: NB100-65935 recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56kD member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, haematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG

• Applications: Flow Cytometry, Immunoprecipitation
• Clone: 3D7
• Conjugate: Unconjugated
• Gene Accession No.: Q9BY15
• Gene Symbols: EMR3
• Immunogen: ARHO-EMR3-CD97 (EGF1) transfectants.
• Quantity: 0.1 mg
• Research Discipline: GPCR, Immunology, Innate Immunity
• Gene ID (Entrez): 84658
• Target Species: Human
• Form: Purified

For Research Use Only