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Arylsulfatase G Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528042

Catalog No. PIPA528042


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Description

Description

PA5-28042 targets Arylsulfatase G in WB applications and shows reactivity with Human samples. The PA5-28042 immunogen is recombit fragment corresponding to a region within amino acids 117 and 388 of Human Arylsulfatase G. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.
Specifications

Specifications

Arylsulfatase G
Polyclonal
Unconjugated
ARSG
Liquid
ARSG
Recombit fragment corresponding to a region within amino acids 117 and 388 of Human Arylsulfatase G
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
0.66 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q96EG1
ASG
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
22901
Documents
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