Asialo GM1 Rabbit anti-Bovine, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA185210
Rabbit anti Bovine Asialo GM1 antibody recognizes bovine asialo-GM1, a neutral glycosphingolipid expressed on the surface on natural killer (NK) cells and come macrophages in mice (Stein-Streilein and Guffee 1986).Asialo ganglio-N-tetraosylceramide (asialo-GM1) is a glycolipid on human, mouse, rat, bovine and hamster cells. Glycolipids such as this sialyated version are defined by the specific transferases that modify the lipid. Glycolipids are targets of immune cell response. Auto-antibodies have also been identified. Additionally these glycolipids can act as co-receptors for pathogens. Asialo-GM1 is present on both NK cells and a subset of monocyte/macrophages from the mouse spleen. Expression is also found on rat and bovine brain, fetal liver and on fetal immature thymocytes. Expression has also been shown to increase with tumor progression.
|4°C or -20°C if preferred|
|PBS with 0.09% sodium azide|
|Asialo ganglio-N-tetraosylceramide; AsialoGM1|
|Native protein, from brain.|
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