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Asialo GM1 Rabbit anti-Bovine, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA185210

Catalog No. PA185210


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Description

Description

Rabbit anti Bovine Asialo GM1 antibody recognizes bovine asialo-GM1, a neutral glycosphingolipid expressed on the surface on natural killer (NK) cells and come macrophages in mice (Stein-Streilein and Guffee 1986).

Asialo ganglio-N-tetraosylceramide (asialo-GM1) is a glycolipid on human, mouse, rat, bovine and hamster cells. Glycolipids such as this sialyated version are defined by the specific transferases that modify the lipid. Glycolipids are targets of immune cell response. Auto-antibodies have also been identified. Additionally these glycolipids can act as co-receptors for pathogens. Asialo-GM1 is present on both NK cells and a subset of monocyte/macrophages from the mouse spleen. Expression is also found on rat and bovine brain, fetal liver and on fetal immature thymocytes. Expression has also been shown to increase with tumor progression.
Specifications

Specifications

Asialo GM1
Polyclonal
Unconjugated
Liquid
Rabbit
IgG
1 mL
4°C or -20°C if preferred
Primary
Bovine
ELISA
5 mg/mL
PBS with 0.09% sodium azide
Asialo ganglio-N-tetraosylceramide; AsialoGM1
Native protein, from brain.
Protein G
RUO
Antibody
Polyclonal
Documents
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