Ataxin 3 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527391
PA5-27391 targets Ataxin 3 in IF and WB applications and shows reactivity with Human samples. The PA5-27391 immunogen is recombit protein fragment corresponding to a region within amino acids 44 and 364 of Human Ataxin 3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal domit neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
|Recombit protein fragment corresponding to a region within amino acids 44 and 364 of Human Ataxin 3|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 10% glycerol and 0.01% thimerosal; pH 7|
|AT3, ATX3, JOS, MJD, MJD1, SCA3, Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal domit, ataxin 3), Machado-Joseph disease protein 1, ataxin 3 variant h, ataxin 3 variant m, ataxin 3 variant ref, ataxin-3, josephin, olivopontocerebellar ataxia 3, spin|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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