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ATF3 Mouse anti-Human, Clone: 7G10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA518444

Catalog No. PIMA518444


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Description

Description

Peptide Sequence: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
Specifications

Specifications

ATF3
Monoclonal
0.5 mg/mL
PBS with no preservative; pH 7.4
P18847
Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3, ATF 3
Mouse
IgG1, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
467
ELISA, Western Blot
7G10
Unconjugated
ATF3
Liquid
ATF3
ATF3 (AAH06322, 1 a.a. ∽ 181 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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