ATF3 Mouse anti-Human, Clone: 7G10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA518444
Peptide Sequence: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ SActivating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
|PBS with no preservative; pH 7.4|
|Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3, ATF 3|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|ATF3 (AAH06322, 1 a.a. ∽ 181 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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