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ATG16L1 Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen OSA00047W

Catalog No. OSA00047W

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Reconstitute with 150 µL of distilled water.

Autophagy related protein 16 L is encoded by the ATG16L gene and is located on chromosome 2 in humans. It is also known as WD30 or IBD10 (Inflammatory Bowel Disease 10). ATG 12 and ATG5 conjugate with each other and undergoes homo oligomerization with ATG16L to form an 800 kDa complex called the Atg16L complex. This complex facilitates coupling or lipidation of LC3 to phosphatidylethanolamine (PE) and this ubiquitin-like conjugation system is a widely used marker for autophagy. However, the ATG 16L complex along with other ATGs like ATG 18 and ATG 21 prevent the premature cleavage of ATG8-PE by the cysteine protease, Atg4 until the autophagosome is deemed complete.
Specifications

Specifications

ATG16L1
Polyclonal
whole serum with no preservative
Q8C0J2
Autophagy-related protein 16-1, APG16L isoforms 1, 2, 3
Rabbit
IgG
RUO
Antibody
Polyclonal
Mouse
Immunohistochemistry, Western Blot
Unconjugated
Atg16l1
Lyophilized
ATG16L1
A synthetic peptide from mouse APG16L conjugated to an immunogenic carrier protein has been used as the antigen
150 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
77040
SDS
Documents
Product Certifications
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