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MilliporeSigma™ anti-ATP-binding cassette transporter-1, ABCA1 (ABC-1) , Clone: AB.H10, ™ (Chemicon™)

Supplier:  MilliporeSigma™ MAB10005/DEL

Encompass

Catalog No. 50-174-712

Item Discontinued This item has been discontinued by Fisher Scientific. Please to view product availability in your area.

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Description

Description

Mutations in the ABCA1 gene are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.

ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting

Specifications

Specifications

ATP-binding cassette transporter-1, ABCA1 (ABC-1)
Unconjugated
Recombinant fragment, corresponding to amino acids 1800-2260 of Human ABCA1.
RUO
Primary
Semi-purified
Monoclonal
Mouse
100 μg
Endocrine/Metabolism
Chicken, Human, Mouse
IgG1
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