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MilliporeSigma™ anti-ATP-binding cassette transporter-1, ABCA1 (ABC-1) , Clone: AB.H10, ™ (Chemicon™) Non-distribution product as customer accommodation.

Manufacturer:  MilliporeSigma™ MAB10005/DEL

Catalog No. 50-174-712

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
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Description

Description

Mutations in the ABCA1 gene are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.

ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Specifications

ATP-binding cassette transporter-1, ABCA1 (ABC-1)
Semi-purified
Recombinant fragment, corresponding to amino acids 1800-2260 of Human ABCA1.
100μg
Endocrine/Metabolism
Monoclonal
Unconjugated
Murine
IgG1
RUO
Primary
Chicken, Human, Murine
SDS
Documents
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