ATP11B Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520996
A suggested positive control is K562 cell lysate. PA5-20996 can be used with blocking peptide PEP-1110.ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
|A 19 amino acid peptide near the amino terminus of human ATP11B.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|ATPIF, ATPIR; ATPase IR; probable phospholipid-transporting ATPase IF|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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