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ATP11B Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520996

Catalog No. PIPA520996


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Description

Description

A suggested positive control is K562 cell lysate. PA5-20996 can be used with blocking peptide PEP-1110.

ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
Specifications

Specifications

ATP11B
Polyclonal
Unconjugated
ATP11B
Liquid
ATP11B
A 19 amino acid peptide near the amino terminus of human ATP11B.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9Y2G3
ATPIF, ATPIR; ATPase IR; probable phospholipid-transporting ATPase IF
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
23200, 76295
Documents
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