ATP2A1, Mouse, Clone: 4B8, Abnova
Mouse monoclonal antibody raised against a partial recombinant ATP2A1.
Manufacturer: Abnova Corporation H00000487M05
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeqSequence: IDRCNYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQ
|ATPase, Ca++ transporting, cardiac muscle, fast twitch 1|
|ATP2A1 (NP_775293, 522 a.a. ∽613 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26kDa|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|In 1X PBS, pH 7.4|
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