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ATP6V0B Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523936

Catalog No. PIPA523936

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c ft., c ft. ft., and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.
Specifications

Specifications

ATP6V0B
Polyclonal
PBS with 0.09% sodium azide
Q99437
ATP6F, HATPL, VMA16, H(+)-transporting two-sector ATPase, subunit F, V-ATPase 21 kDa proteolipid subunit, V-ATPase subunit c′′, V-type proton ATPase 21 kDa proteolipid subunit, vacuolar ATP synthase 21 kDa proteolipid subunit, vacuolar proton pump 21 kDa proteolipid subunit, vacuol
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
533
Immunohistochemistry, Western Blot
Unconjugated
ATP6V0B
Liquid
ATP6V0B
KLH conjugated synthetic peptide between 104-131 amino acids from the central region of human ATP6V0B
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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