V-ATPase A Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526779
This antibody is predicted to react with bovine, mouse and porcine based on sequence homology.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c ft., c ft., and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues.
|PBS with 0.09% sodium azide|
|ATP6A1, ATP6V1A1, HO68, VA68, VPP2, Vma1, ATPase, H+ transporting, lysosomal, subunit A1, H(+)-transporting two-sector ATPase, subunit A, H+-transporting ATPase chain A, vacuolar (VA68 type), V-ATPase 69 kDa subunit 1, V-ATPase A subunit 1, V-ATPase subunit A, V-type proton ATPase catalytic subunit A, v|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 441-468 amino acids from the central region of human ATP6V1A|
|Antigen affinity chromatography|
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