V-ATPase H Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA525106
This antibody is predicted to react with bovine and porcine based on sequence homology.ATP6V1H encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c ft., c ft., and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the regulatory H subunit of the V1 domain which is required for catalysis of ATP but not the assembly of V-ATPase.
|PBS with 0.09% sodium azide|
|MSTP042, NBP1, SFD, SFDalpha, SFDbeta, VMA13, V-ATPase 50/57 kDa subunits, V-ATPase H subunit, V-ATPase subunit H, V-type proton ATPase subunit H, nef-binding protein 1, protein VMA13 homolog, vacuolar ATP synthase subunit H, vacuolar ATPase subunit H, vacuolar proton pump H subunit, vacuolar proton pump subu|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human ATP6V1H|
|Antigen affinity chromatography|
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