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hnRNP D Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527534

Catalog No. PIPA527534


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Description

Description

PA5-27534 targets AUF1 in WB applications and shows reactivity with Human and mouse samples. The PA5-27534 immunogen is recombit fragment corresponding to a region within amino acids 138 and 355 of Human AUF1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
Specifications

Specifications

hnRNP D
Polyclonal
Unconjugated
HNRNPD
Liquid
HNRNPD
Recombit fragment corresponding to a region within amino acids 138 and 355 of Human AUF1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
0.45 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Q14103, Q60668
AUF1, AUF1A, HNRPD, P37, hnRNPD0, ARE-binding protein AUFI, type A, heterogeneous nuclear ribonucleoprotein D0, hnRNP D0
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
11991, 3184
Documents
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