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Aurora A Mouse anti-Bovine, Canine, Equine, Human, Mouse, Non-human primate, Porcine, Rat, Clone: 35C1, Invitrogen™ Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen 458900

Catalog No. 45-890-0


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Description

Description

Aurora A is a 46 kDa protein that plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Multiple transcript variants encoding the same protein have been found for this gene. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.

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Specifications

Specifications

Aurora A
Monoclonal
0.5 mg/mL
PBS with 0.1% sodium azide; pH 7.4
Q2TA06, O14965, P97477, A5GFW1, P59241
AIK, ARK1, AYK1, Aurora-A, Aurora-family kinase 1, Aurora-related kinase 1, Aurora/IPL1-related kinase 1, BTAK, Breast-tumor-amplified kinase, EC 2.7.11.1, IAK1, Ipl1- and aurora-related kinase 1, STK15, STK6, Serine/threonine kinase 15, Serine/threonine
Mouse
IgG1
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100050161, 20878, 261730, 485940, 504437, 574063, 6790
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
35C1
Unconjugated
AURKA
Liquid
AURKA
Recombit protein derived from the full length of human Aurora A Kinase protein
Protein A
RUO
Antibody
Monoclonal
Bovine, Canine, Equine, Human, Mouse, Non-human primate, Porcine, Rat
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