Aurora A Mouse anti-Bovine, Canine, Equine, Human, Mouse, Non-human primate, Porcine, Rat, Clone: 35C1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen 458900
DescriptionAurora A is a 46 kDa protein that plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Multiple transcript variants encoding the same protein have been found for this gene. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.
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|PBS with 0.1% sodium azide; pH 7.4|
|Q2TA06, O14965, P97477, A5GFW1, P59241|
|AIK, ARK1, AYK1, Aurora-A, Aurora-family kinase 1, Aurora-related kinase 1, Aurora/IPL1-related kinase 1, BTAK, Breast-tumor-amplified kinase, EC 220.127.116.11, IAK1, Ipl1- and aurora-related kinase 1, STK15, STK6, Serine/threonine kinase 15, Serine/threonine|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|100050161, 20878, 261730, 485940, 504437, 574063, 6790|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|Recombit protein derived from the full length of human Aurora A Kinase protein|
|Bovine, Canine, Equine, Human, Mouse, Non-human primate, Porcine, Rat|
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