B4GALT2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526483
This antibody is predicted to react with rat based on sequence homology.B4GALT2 is one of type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue.
|PBS with 0.09% sodium azide|
|B4Gal-T2, B4Gal-T3, beta4Gal-T2, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2, UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2, beta-1,4-Gal|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 290-318 amino acids from the C-terminal region of human B4GALT2|
|Antigen affinity chromatography|
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