anti-BACE-1, Polyclonal, Novus Biologicals
Rabbit Polyclonal Antibody
Manufacturer: Novus Biologicals NBP177307
DescriptionBACE-1 Polyclonal antibody specifically detects BACE-1 in Human, Mouse samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
|Western Blot 0.5-1 ug/ml, ELISA 1:100-1:2000, Immunohistochemistry 2.5 ug/ml, Immunocytochemistry/Immunofluorescence 10 ug/ml, Immunohistochemistry-Paraffin 2.5 ug/ml|
|APP beta-secretase, ASP2, Aspartyl protease 2, BACEAsp 2, beta-secretase 1, beta-secretase 1 precursor variant 1, beta-site amyloid beta A4 precursor protein-cleaving enzyme, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1, EC 3.4.23, EC 22.214.171.124, FLJ90568, HSPC104, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2, transmembrane aspartic proteinase Asp2|
|Ion exchange chromatography|
|Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.|
|Human BACE-1 has 6 isoforms, including isoform A (501aa, 55.8kD), isoform B (476aa, 52.9kD), isoform C (457aa, 51.1kD), isoform D (432aa, 48.2kD), isoform 5 (401aa, 45kD) and isoform 6 (376aa, 42.2kD). This antibody detects all human isoforms. Mouse BACE-1 has only 1 isoform (501aa, 55.7kD). Rat BACE-1 has only one isoform identified so far (501aa, 55.8kD).|
|ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.02% Sodium Azide|
|Ion Exchange Chromatography|
|Antibody was raised against a peptide corresponding to 17 amino acids at the carboxy terminus of human BACE. The immunogen is located within the last 50 amino acids of BACE.|
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