Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Bacillus anthracis Spore Antigen, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA128944

Catalog No. PA128944

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium Bacillus anthracis, the causative agent of anthrax. Anthrax toxin is composed of a cell-binding protein, known as protective antigen (PA), and two enzyme components, called edema factor (EF) and lethal factor (LF). These three protein components act together to impart their physiological effects. Assembled complexes containing the toxin components are endocytosed. In the endosome, the enzymatic components of the toxin translocate into the cytoplasm of a target cell. Once in the cytosol, the enzymatic components of the toxin disrupts various immune cell functions, namely cellular signaling and cell migration. The toxin may even induce cell lysis, as is observed for macrophage cells. Anthrax toxin allows the bacteria to evade the immune system, proliferate, and ultimately kill the host animal. Research on anthrax toxin also provides insight into the generation of macromolecular assemblies, and on protein translocation, pore formation, endocytosis, and other biochemical processes.

PA1-28944 detects Bacillus anthracis spore antigen from bacteria samples.PA1-28944 has been successfully used in immunofluorescence applications.The PA1-28944 immunogen is: Purified spores of Bacillus cereus (ATCC 11778) and Bacillus subtilis (ATCC 9372).
Specifications

Specifications

Bacillus anthracis Spore Antigen
Polyclonal
Unconjugated
Purified
Rabbit
IgG
1mL
Store at -20°C
Primary
Bacteria
Immunocytochemistry, Immunofluorescence
4mg/mL
PBS with 0.1% sodium azide; pH 7.2
B. anthracis Spore, Bacillus anthracis Spore, Anthrax Spore
Purified spores of Bacillus cereus (ATCC 11778) and Bacillus subtilis (ATCC 9372).
Protein A
RUO
Antibody
Polyclonal
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit