Bacillus anthracis Spore Antigen, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA128944
Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium Bacillus anthracis, the causative agent of anthrax. Anthrax toxin is composed of a cell-binding protein, known as protective antigen (PA), and two enzyme components, called edema factor (EF) and lethal factor (LF). These three protein components act together to impart their physiological effects. Assembled complexes containing the toxin components are endocytosed. In the endosome, the enzymatic components of the toxin translocate into the cytoplasm of a target cell. Once in the cytosol, the enzymatic components of the toxin disrupts various immune cell functions, namely cellular signaling and cell migration. The toxin may even induce cell lysis, as is observed for macrophage cells. Anthrax toxin allows the bacteria to evade the immune system, proliferate, and ultimately kill the host animal. Research on anthrax toxin also provides insight into the generation of macromolecular assemblies, and on protein translocation, pore formation, endocytosis, and other biochemical processes.PA1-28944 detects Bacillus anthracis spore antigen from bacteria samples.PA1-28944 has been successfully used in immunofluorescence applications.The PA1-28944 immunogen is: Purified spores of Bacillus cereus (ATCC 11778) and Bacillus subtilis (ATCC 9372).
|Bacillus anthracis Spore Antigen|
|Store at -20°C|
|PBS with 0.1% sodium azide; pH 7.2|
|B. anthracis Spore, Bacillus anthracis Spore, Anthrax Spore|
|Purified spores of Bacillus cereus (ATCC 11778) and Bacillus subtilis (ATCC 9372).|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok