BAF53A, Polyclonal, Invitrogen
Chicken Polyclonal Antibody
Manufacturer: Invitrogen PA129471
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.PA1-29471 detects BAF53A from mouse, human samples.PA1-29471 has been successfully used in Western blot applications.The PA1-29471 immunogen is: Recombinant fragment, corresponding to amino acids 1-429 of Human BAF53A.
|Recombinant fragment, corresponding to amino acids 1-429 of Human BAF53A.|
|Antigen affinity chromatography|
|PBS with no preservative|
|ACTL6, ARPN-BETA, Arp4, BAF53A, INO80K, MGC5382|
|Store at -20°C|
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