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BAG2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527701

Catalog No. PIPA527701


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Description

Description

PA5-27701 targets BAG2 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27701 immunogen is recombit fragment corresponding to a region within amino acids 1 and 211 of Human BAG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Specifications

Specifications

BAG2
Polyclonal
Unconjugated
BAG2
Liquid
BAG2
Recombit fragment corresponding to a region within amino acids 1 and 211 of Human BAG2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
O95816
BAG-2, dJ417I1.2, BAG family molecular chaperone regulator 2, BAG-family molecular chaperone regulator-2, bcl-2-associated athanogene 2, dJ417I1.2 (BAG-family molecular chaperone regulator 2)
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
9532
Documents
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