BAK Goat anti-Human, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA19014
This antibody is predicted to react with mouse, porcine and rat based on sequence homology.The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
|Synthetic peptide corresponding to the N terminus amino acids ASGQGPGPPRQE.|
|Antigen affinity chromatography|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|BAK1; BCL2-antagonist/killer 1; BAK; CDN1; BCL2L7; cell death inhibitor 1; apoptosis regulator BAK; Bcl-2 homologous antagonist/killer|
|-20° C, Avoid Freeze/Thaw Cycles|
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