BAK Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527093
PA5-27093 targets BAK1 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27093 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 44 of Human BAK1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
|Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human BAK1|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 20% glycerol and 0.01% thimerosal; pH 7|
|BAK, BAK-LIKE, BCL2L7, CDN1, BCL2-like 7 protein, apoptosis regulator BAK, bcl-2 homologous antagonist/killer, bcl-2-like protein 7, bcl2-L-7, pro-apoptotic protein BAK|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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