Bcl-10 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA112513
A suggested positive control for this product is Raji whole cell lysate.BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.
|PBS with 0.02% sodium azide|
|B-cell CLL/lymphoma 10, Bcl-10 CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER|
|-20° C, Avoid Freeze/Thaw Cycles|
|Synthetic peptide corresponding to residues 5-19 of human BCL-10.|
|Antigen affinity chromatography|
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