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BCL2A1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA511376

Catalog No. PIPA511376

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
Specifications

Specifications

BCL2A1
Polyclonal
PBS with 0.09% sodium azide
Q16548
Human Bcl2-related Protein A1, BFL1, Hematopoietic-specific early response protein, GRS protein
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
597
Immunohistochemistry, Western Blot
Unconjugated
BCL2A1
Liquid
BCL2A1
KLH conjugated synthetic peptide between 30-65 amino acids from human BCL2A1 (A1)
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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