BCL2A1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA524561
DescriptionBcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
|PBS with 0.09% sodium azide|
|ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1, bcl-2-like protein 5, bcl-2-related protein A1, bcl2-L-5, hematopoietic BCL2-related protein A1, hemopoietic-specific early response protein, protein BFL-1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|KLH conjugated synthetic peptide between 53-81 amino acids from the central region of human BCL2A1|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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