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BCL6 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527390

Catalog No. PIPA527390


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Description

Description

PA5-27390 targets BCL6 in IHC (P), ChIP, IP and WB applications and shows reactivity with Human samples. The PA5-27390 immunogen is recombit fragment corresponding to a region within amino acids 160 and 415 of Human BCL6. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Specifications

Specifications

BCL6
Polyclonal
Unconjugated
BCL6
Liquid
BCL6
Recombit fragment corresponding to a region within amino acids 160 and 415 of Human BCL6
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
ChIP assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
P41182, P41183
BCL5, BCL6A, LAZ3, ZBTB27, ZNF51, B-cell lymphoma 5 protein, B-cell lymphoma 6 protein, B-cell lymphoma 6 protein transcript, BCL-5, BCL-6, cys-his2 zinc finger transcription factor, lymphoma-associated zinc finger gene on chromosome 3, protein LAZ-3, zinc finger and BTB domain-containing protein
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
12053, 604
Documents
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