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BCL7A Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527123

Catalog No. PIPA527123


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Description

Description

PA5-27123 targets BCL7A in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27123 immunogen is synthetic peptide corresponding to a region within amino acids 148 and 210 of Human BCL7A. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

BCL7A
Polyclonal
Unconjugated
BCL7A
Liquid
BCL7A
Synthetic peptide corresponding to a region within amino acids 148 and 210 of Human BCL7A
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Q4VC05, Q9CXE2
BCL7, B-cell CLL/lymphoma 7 protein family member A, B-cell CLL/lymphoma-7
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
605, 77045
Documents
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