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BDNF Polyclonal Antibody, Invitrogen™

BDNF Antibody, PA1-18370, from Invitrogen™. Species Reactivity: Human, Mouse, Rat; Applications: ELISA, Immunohistochemistry.

Manufacturer:  Invitrogen PA118370

Catalog No. 01-670-622


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Specifications

Description

BDNF Antibody, PA1-18370, from Invitrogen. Species Reactivity: Human, Mouse, Rat; Applications: ELISA, Immunohistochemistry.

BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rat
Isotype: IgG
Immunogen: A synthetic peptide corresponding to human BDNF protein aa 129-138 (HSDPARRGEL) conjugated to KLH
Formulation: 20µg purified antibody (1mg/mL) and no preservative
Synonyms: Brain-derived neurotrophic factor, Abrineurin
Uniprot Accession: P21237, P23363, P23560
Entrez GeneID: 12064, 24225, 627
Gene Symbol: BDNF
The immunogenic sequence is highly conserved among most mammalian species. This antibody exhibits less than 0.1% cross reactivity with mouse NGF, recombinant human NT3 and NT4/5 by dot blot analysis. Reconstitute with 20 ul of distilled water.
Description & Specifications

Specifications

BDNF
Unlabeled
P21237, P23363, P23560
Brain-derived neurotrophic factor, Abrineurin
Rabbit
IgG
avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Polyclonal
Human,Murine,Rat
ELISA,Immunohistochemistry
20μg purified antibody (1mg/mL) and no preservative
Purified
BDNF
A synthetic peptide corresponding to human BDNF protein aa 129-138 (HSDPARRGEL) conjugated to KLH
20μg
Primary
12064, 24225, 627
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  • Purchase any three Invitrogen™ Antibodies and receive a fourth antibody at no additional cost. This is an NLSU exclusive offer. You must apply and qualify for the program to be eligible.

    06-30-2018

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