anti-BDNF Polyclonal, Thermo Scientific™

BDNF Polyclonal Ab PA1-18357 from Thermo Scientific™ specifically detects BDNF in Hu, Ms and Rt samples, and it is validated for ELISA, IHC, Inhibition Assays and WB

Manufacturer: Invitrogen PA118363

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Catalog No. 01-670-615

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    Specifications

    Antigen BDNF
    Applications Enzyme Linked Immunosorbent Assay,Immunohistochemistry,Inhibition Assays,Western Blot
    Conjugate Unlabeled
    Cross Reactivity Human,Rat
    Format Purified
    Formulation 500μg purified antibody (1mg/mL) and no preservative
    Gene Accession No. P23363, P23560
    Gene Alias Brain-derived neurotrophic factor, Abrineurin
    Gene Symbols BDNF
    Host Species Sheep
    Immunogen Recombinant human BDNF.
    Isotype IgG
    Quantity 500μg
    Species Reactivity Human, Rat
    Storage Requirements avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 24225, 627

    BDNF Polyclonal Ab PA1-18357 from Thermo Scientific™ specifically detects BDNF in Hu, Ms and Rt samples, and it is validated for ELISA, IHC, Inhibition Assays and WB

    The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
    Host Species: Sheep
    Cross Reactivity: Human, Rat
    Isotype: IgG
    Immunogen: Recombinant human BDNF.
    Formulation: 500µg purified antibody (1mg/mL) and no preservative
    Synonyms: Brain-derived neurotrophic factor, Abrineurin
    Uniprot Accession: P23363, P23560
    Entrez GeneID: 24225, 627
    Gene Symbol: BDNF
    By ELISA, this antibody exhibits a cross-reactivity of less than 1% to recombinant human BDNF, NT3 and NT4/5. Use at 1-10µg/ml for inhibition of biological activity in vitro. Use neat for in vivo studies at 2-10µg/ml (ED50). Reconstitute with 500 ul of distilled water. After reconstitution keep aliquots at -20º for a higher stability, and at 4ºC with an appropriate antibacterial agent.

  • Description & Specifications

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