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Beclin 1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA118287

Catalog No. 01-670-540


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Description

Description

PA1-18287 detects Beclin-1 from human samples. PA1-18287 has been successfully used in immunohistochemistry and immunofluorescence procedures. The PA1-18287 immunogen is a synthetic peptide corresponding to the C-terminal residues of human Beclin-1, conjugated to Blue Carrier Protein. The sequence is 100% conserved in mouse and rat. Reconstitute with 100 µL of distilled water.

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
Specifications

Specifications

Beclin 1
Polyclonal
whole serum with no preservative
Q14457
BECN1, APG6, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197
Rabbit
IgG
RUO
Antibody
Polyclonal
Human
Immunofluorescence, Immunohistochemistry
Unconjugated
BECN1
Lyophilized
BECN1
Synthetic peptide corresponding to the C-terminal residues of human Beclin-1.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8678
Documents
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