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Bestrophin 2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA526253

Catalog No. PIPA526253

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with chicken and mouse based on sequence homology.

Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate. The Best2 gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3 ft. ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in the Best2 gene is associated with vitelliform macular dystrophy. The Best2 gene is mainly expressed in the retinal pigment epithelium and colon. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.
Specifications

Specifications

Bestrophin 2
Polyclonal
PBS with 0.09% sodium azide
Q8NFU1
VMD2L1, VMD2-like gene 1, bestrophin-2, vitelliform macular dystrophy 2-like 1, vitelliform macular dystrophy 2-like protein 1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
54831
Immunohistochemistry, Western Blot
Unconjugated
BEST2
Liquid
BEST2
KLH conjugated synthetic peptide between 374-403 amino acids from the C-terminal region of human BEST2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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