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beta-2 Adrenergic Receptor Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527083

Catalog No. PIPA527083


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Description

Description

PA5-27083 targets beta 2 Adrenergic Receptor in immunohistochemistry (paraffin) and Western blot applications and shows reactivity with Human and Rat samples. The PA5-27083 immunogen is synthetic peptide corresponding to a region within amino acids 340 and 413 of Human beta 2 Adrenergic Receptor. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Specifications

Specifications

beta-2 Adrenergic Receptor
Polyclonal
Unconjugated
ADRB2
Liquid
ADRB2
Synthetic peptide corresponding to a region within amino acids 340 and 413 of Human beta 2 Adrenergic Receptor
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Rat
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
P07550, P10608
ADRB2R, ADRBR, B2AR, BAR, BETA2AR, beta-2 adrenergic receptor, beta-2 adrenoceptor, beta-2 adrenoreceptor, catecholamine receptor
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
154, 24176
Documents
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