Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

beta Actin Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1183

Catalog No. PIPA1183


Add to cart

Description

Description

By Western blot, PA1-183 detects a prominent ~42kD protein in human, mouse, non-human primate, and rat whole cell lysates. For visualization of actin filaments by immunofluorescence, fixation and permeabilization with methanol is required.

Beta actin is one of six actin isoforms which have been identified. Beta actin is a non-muscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. There are six different actin isoforms in human. The beta isoform of actin, along with gamma actin, coexist in most cell types as components of the cyto-skeleton. Beta actins are cytoplasmic proteins ubuquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of two stranded helix. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Because beta actin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting. Antibodies to beta-actin provide a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton.
Specifications

Specifications

beta Actin
Polyclonal
Unconjugated
ACTB
Liquid
ACTB
Purified full-length recombit human beta-actin expressed in E. coli
Protein G
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate, Rat
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
1 mg/mL
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
P60709, P60710, P60711
Actin, ACTB, Atcb
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
11461, 60, 81822
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit