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beta Lactamase Mouse anti-Bacteria, Clone: 8A5.A10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA110712

Catalog No. 01-671-942


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Description

Description

MA1-10712 detects beta Lactamase from E. coli samples. MA1-10712 has been successfully used in ELISA and Western blot applications. The MA1-10712 immunogen is 5-His-tagged TEM-1 beta-lactamase.

The beta lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta lactams are structurally related through the presence of a core beta lactam ring. Bacterial resistance to beta lactams continues to increase, primarily due to the production of beta lactamases. Beta lactamases catalyze the hydrolysis of the beta lactam bond, which destroys antibacterial activity. Bacteria that produce TEM type or SHV type beta lactamases have point mutations in structural genes that have extended the substrate specificity of these beta lactamases. As a result, many of the beta lactamase producing Gram negative pathogens have become multidrug resistant.
Specifications

Specifications

beta Lactamase
Monoclonal
1.8 mg/mL
PBS with no preservative; pH 7.4
blaCTX-M-14; beta-lactamase CTX-M-14; FLJ14902; G24; MRPL56
5′-His-tagged TEM-1 beta-lactamase.
Protein G
RUO
Antibody
Monoclonal
ELISA, Western Blot
8A5.A10
Unconjugated
Liquid
Mouse
IgG1
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
Bacteria
Documents
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