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beta Synuclein Sheep anti-Human, Rat, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA118261

Catalog No. 01-670-514

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Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.

PA1-18261 detects beta Synuclein from human and rat samples.PA1-18261 has been successfully used in immunohistochemistry procedures.The PA1-18261 immunogen is a synthetic peptide corresponding to residues I(108) E P L M E P E G S Y E D P P Q E(125) of human beta synuclein protein, conjugated to diphteria toxid.Reconstitute with 100 ul of distilled water.


beta Synuclein
Synthetic peptide corresponding to residues I(108) E P L M E P E G S Y E D P P Q E(125) of human beta synuclein protein.
Affinity chromatography
Human, Rat
1 mg/mL
Antibody with no preservative
Q16143, Q63754
100 μg
-20° C, Avoid Freeze/Thaw Cycles
113893, 6620
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