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BFAR Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520894

Catalog No. PIPA520894


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Description

Description

A suggested positive control is human kidney tissue lysate. PA5-20894 can be used with blocking peptide PEP-1008.

The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors ( ft.extrinsic pathway ft.) as well as mitochondria-dependent apoptosis ( ft.intrinsic pathway ft.). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.
Specifications

Specifications

BFAR
Polyclonal
Unconjugated
BFAR
Liquid
BFAR
A 14 amino acid peptide near the carboxy terminus of human BFAR.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9NZS9, Q8R079, Q5PQN2
BAR, RNF47; RING finger protein 47; bifunctional apoptosis inhibitor
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
304709, 51283, 67118
Documents
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