Blimp-1 Rat anti-Mouse, PE-CF594, Clone: 5E7, BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 564269
The 5E7 monoclonal antibody specifically binds to mouse B lymphocyte-induced maturation protein 1 (Blimp-1). Blimp-1 is a 98 kDa zinc finger-containing protein that is encoded by the Prdm1 gene and functions as a transcriptional repressor. Blimp-1 is essential for regulating the terminal differentiation of activated B cells into plasma cells. In this process, Blimp-1 suppresses genes involved in B cell proliferation, such as Myc and Bcl6 . It controls other genes, such as
This antibody is conjugated to BD Horizon PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red (eg 610/20-nm filter).
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Flow Cytometry, Immunocytochemistry|
|Prdm1; PR domain zinc finger protein 1; Blimp1; PRDI-BF1; ZNFPR1A1|
|Mouse Blimp-1 Recombinant Protein|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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